EEF1D and CD48

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1D	CD48
Gene Name		eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	CD48 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Plasma Membrane Integral Component Of Plasma Membrane Membrane Anchored Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Translation Elongation Factor Activity Signal Transducer Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding	Receptor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Signal Transduction Gene Expression Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Protein Metabolic Process	Defense Response Blood Coagulation Leukocyte Migration
Pathways		Translation Eukaryotic Translation Elongation	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		33 interactors: ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS ERP27 FOS FRA10AC1 GARS HEXDC KARS KTN1 MAP1B NR2F1 POT1 PRKCA RELA RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 VARS	10 interactors: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		1936	962
HPRD ID		00560	00177
Ensembl ID		ENSG00000104529	ENSG00000117091
Uniprot IDs		B2RAR6 D3DWK1 P29692	P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Metabolic Process Movement Of Cell Or Subcellular Component Response To External Stimulus Negative Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Axonogenesis Regulation Of Telomere Maintenance Via Telomerase Axon Development Negative Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Cellular Metabolic Process Toll-like Receptor 10 Signaling Pathway Cell Differentiation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Apoptotic Process Neuron Projection Morphogenesis Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death MyD88-independent Toll-like Receptor Signaling Pathway Diadenosine Tetraphosphate Biosynthetic Process Regulation Of Telomere Maintenance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Viral Genome Replication Cell Morphogenesis Involved In Differentiation Negative Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Schwann Cell Differentiation Neuron Projection Development Neurotrophin TRK Receptor Signaling Pathway Cell Projection Morphogenesis Nucleobase-containing Compound Metabolic Process Axon Guidance Chemotaxis Neurotrophin Signaling Pathway Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Histone H4 Acetylation	Regulation Of Defense Response To Virus By Virus Blood Coagulation Hemostasis Leukocyte Migration Regulation Of Body Fluid Levels Wound Healing T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation T Cell Costimulation Cell Activation Regulation Of T Cell Activation Regulation Of Defense Response To Virus Positive Regulation Of Cell Activation Immune System Process Response To Wounding Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Signaling Antigen Receptor-mediated Signaling Pathway Cell Communication Regulation Of Cell Activation Leukocyte Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Single Organismal Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Platelet Activation Cellular Response To Stimulus Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immune Response Response To Stress Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Production Positive Regulation Of Intracellular Signal Transduction Cell Migration Natural Killer Cell Activation Cell Motility Positive Regulation Of Immune System Process
Tagcloud ?			advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Difference) ?			advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Intersection) ?