GNAZ and NMT1

Number of citations of the paper that reports this interaction (PMID 2153964)
57

Data Source:
HPRD (in vitro)

		GNAZ	NMT1
Gene Name		guanine nucleotide binding protein (G protein), alpha z polypeptide	N-myristoyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Cytosol Heterotrimeric G-protein Complex Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Extrinsic Component Of Membrane Cell Junction
	Molecular Function	GTPase Activity Signal Transducer Activity Receptor Signaling Protein Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding G-protein Coupled Serotonin Receptor Binding Metal Ion Binding	Glycylpeptide N-tetradecanoyltransferase Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Intracellular Signal Transduction	In Utero Embryonic Development Apoptotic Process Phototransduction, Visible Light Viral Process Rhodopsin Mediated Signaling Pathway N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways		Signaling by GPCR GPCR downstream signaling PLC beta mediated events G alpha (s) signalling events G-protein activation Opioid Signalling G alpha (z) signalling events G alpha (i) signalling events G-protein mediated events	Inactivation, recovery and regulation of the phototransduction cascade HIV Life Cycle Visual phototransduction Activation, myristolyation of BID and translocation to mitochondria The phototransduction cascade HIV Infection Programmed Cell Death Diseases associated with visual transduction Late Phase of HIV Life Cycle Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		15 interactors: ADORA1 APP DRD2 DRD5 EYA1 EYA2 NMT1 NUCB1 OPRD1 PRKCD RAP1GAP RGS10 RGS19 RGS20 RGS7	14 interactors: ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53
Entrez ID		2781	4836
HPRD ID		00746	01187
Ensembl ID		ENSG00000128266	ENSG00000136448
Uniprot IDs		P19086 Q8IY73 Q8N652	P30419
PDB IDs			1RXT 3IU1 3IU2 3IWE 3JTK
Enriched GO Terms of Interacting Partners?		Termination Of Signal Transduction Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Signaling Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Regulation Of Catalytic Activity Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Hydrolase Activity Cell Surface Receptor Signaling Pathway Negative Regulation Of Signal Transduction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Blood Pressure Regulation Of Metabolic Process Histone Dephosphorylation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Response To Stimulus Signal Transduction Associative Learning Response To Abiotic Stimulus Cognition Signaling Regulation Of Systemic Arterial Blood Pressure Synaptic Transmission, Dopaminergic Neurological System Process Cell Communication Negative Regulation Of Synaptic Transmission, Glutamatergic Adult Locomotory Behavior Apoptotic Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of Receptor Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dephosphorylation Regulation Of GTPase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Circadian Rhythm Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Renal Sodium Excretion Regulation Of Cellular Process Learning Regulation Of Anion Transport Regulation Of Excretion	Regulation Of Protein Localization Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Catalytic Activity Blood Coagulation Hemostasis Regulation Of Intracellular Transport T Cell Costimulation Regulation Of Body Fluid Levels Wound Healing Cellular Response To Platelet-derived Growth Factor Stimulus Response To Abiotic Stimulus Regulation Of Protein Transport Response To Platelet-derived Growth Factor Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Wounding Intracellular Signal Transduction Regulation Of Cellular Component Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Axon Guidance Negative Regulation Of Hydrolase Activity Cellular Response To Lipopolysaccharide Regulation Of Apoptotic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Cellular Response To Molecule Of Bacterial Origin Regulation Of Cell Proliferation Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cellular Response To Organonitrogen Compound Negative Regulation Of Programmed Cell Death Regulation Of Protein Oligomerization Regulation Of Cell Activation Cellular Response To Acid Chemical Regulation Of Cell Death Positive Regulation Of Leukocyte Apoptotic Process Regulation Of Platelet Activation Response To Drug Negative Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Calcium Ion Transport Platelet Activation Anatomical Structure Morphogenesis Axonogenesis Protein Autophosphorylation
Tagcloud ?		adbrk2 alg9 arntl dpysl2 drd3 dusp6 famine gad1 gch1 grin1 grin2b gsk3b hip1r homoeostasis hspa5 impa2 kcnq2 per3 pik3c3 pip5k2a plcg1 rgs4 shuts slc6a3 slc6a4 sybl1 synj1 timeless wfs1	c2 cdc25p cys639 elongation fission g2 hect intensified lacks ligases overlaps owing polar pombe pub1 pub1delta pub1p pub2 pub2ca pub2p pub3p replaced rsp5 schizosaccharomyces shares starvation thiol ubiquitinated ww
Tagcloud (Difference) ?		adbrk2 alg9 arntl dpysl2 drd3 dusp6 famine gad1 gch1 grin1 grin2b gsk3b hip1r homoeostasis hspa5 impa2 kcnq2 per3 pik3c3 pip5k2a plcg1 rgs4 shuts slc6a3 slc6a4 sybl1 synj1 timeless wfs1	c2 cdc25p cys639 elongation fission g2 hect intensified lacks ligases overlaps owing polar pombe pub1 pub1delta pub1p pub2 pub2ca pub2p pub3p replaced rsp5 schizosaccharomyces shares starvation thiol ubiquitinated ww
Tagcloud (Intersection) ?