SHANK2 and DLGAP3

Number of citations of the paper that reports this interaction (PMID 10527873)
22

Data Source:
BioGRID (two hybrid)

		SHANK2	DLGAP3
Gene Name		SH3 and multiple ankyrin repeat domains 2	discs, large (Drosophila) homolog-associated protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Cell Junction Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	Postsynaptic Density Cell Junction Postsynaptic Membrane
	Molecular Function	Protein Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Ionotropic Glutamate Receptor Binding	Beta-amyloid Binding Protein Binding
	Biological Process	Synapse Assembly Learning Memory Adult Behavior Social Behavior Exploration Behavior Long-term Synaptic Potentiation Long Term Synaptic Depression Vocalization Behavior	Cell-cell Signaling
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		15 interactors: ARHGEF7 BAI2 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNM2 LPHN1 LPHN2 SHARPIN SLC9A3 SSTR2	8 interactors: DLG1 DLG3 DLG4 DLGAP1 PTK2 PTK2B SHANK2 SHANK3
Entrez ID		22941	58512
HPRD ID		04479	18935
Ensembl ID		ENSG00000162105	ENSG00000116544
Uniprot IDs		C0SPH0 Q9UPX8	O95886
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Signaling Cell Communication Synaptic Transmission Nervous System Development Neuron Projection Morphogenesis Dendritic Spine Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Cell Morphogenesis Focal Adhesion Assembly Neuron Development Cell Morphogenesis Adherens Junction Assembly Lamellipodium Organization Neuron Differentiation Cell-substrate Junction Assembly Cell Projection Organization Endocytosis Regulation Of Cellular Component Organization Regulation Of Axon Extension Negative Regulation Of Membrane Tubulation Post-Golgi Vesicle-mediated Transport Adherens Junction Organization System Development Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Lamellipodium Morphogenesis Generation Of Neurons Synaptic Vesicle Transport Neurogenesis Somatostatin Signaling Pathway Regulation Of Cell Size Regulation Of Cell Projection Organization Dendrite Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Cell Development Multicellular Organismal Development Axonogenesis Maintenance Of Apical/basal Cell Polarity Regulation Of Lamellipodium Morphogenesis Regulation Of Axonogenesis Regulation Of Synaptic Plasticity Cellular Component Assembly G-protein Coupled Receptor Signaling Pathway Anatomical Structure Development Receptor Localization To Synapse Dendritic Spine Maintenance	Receptor Localization To Synapse Receptor Clustering Synaptic Transmission Vocalization Behavior Protein Localization To Synapse Positive Regulation Of Synaptic Transmission Neuron Projection Development Establishment Or Maintenance Of Apical/basal Cell Polarity Cell-cell Signaling Positive Regulation Of Excitatory Postsynaptic Membrane Potential Neuron Development Regulation Of Synaptic Plasticity Positive Regulation Of Membrane Potential Social Behavior Establishment Or Maintenance Of Cell Polarity Neuron Differentiation Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Nervous System Development Neuron Projection Morphogenesis Nucleotide Phosphorylation Regulation Of Membrane Potential Regulation Of Excitatory Postsynaptic Membrane Potential Cell Morphogenesis Involved In Differentiation Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Postsynaptic Membrane Potential Regulation Of Synaptic Transmission Synapse Assembly Generation Of Neurons Signal Complex Assembly Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Protein Localization To Membrane Axon Guidance Cell Development Response To External Stimulus Dendritic Spine Morphogenesis Phosphorylation Membrane Depolarization Regulation Of Receptor Activity Regulation Of Ion Transmembrane Transport Cellular Component Assembly Cell Morphogenesis Learning Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cytoskeleton Organization Regulation Of Cytoskeleton Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Tagcloud ?		acetylation address carbamylated cepo display e1a epigenetic epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet
Tagcloud (Difference) ?		acetylation address carbamylated cepo display e1a epigenetic epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet
Tagcloud (Intersection) ?