SHANK2 and BAI2

Number of citations of the paper that reports this interaction (PMID 10964907)
14

Data Source:
HPRD (two hybrid)

		SHANK2	BAI2
Gene Name		SH3 and multiple ankyrin repeat domains 2	brain-specific angiogenesis inhibitor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Cell Junction Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Ionotropic Glutamate Receptor Binding	G-protein Coupled Receptor Activity
	Biological Process	Synapse Assembly Learning Memory Adult Behavior Social Behavior Exploration Behavior Long-term Synaptic Potentiation Long Term Synaptic Depression Vocalization Behavior	G-protein Coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		15 interactors: ARHGEF7 BAI2 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNM2 LPHN1 LPHN2 SHARPIN SLC9A3 SSTR2	8 interactors: ARHGAP1 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13
Entrez ID		22941	576
HPRD ID		04479	04063
Ensembl ID		ENSG00000162105	ENSG00000121753
Uniprot IDs		C0SPH0 Q9UPX8	O60241
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Signaling Cell Communication Synaptic Transmission Nervous System Development Neuron Projection Morphogenesis Dendritic Spine Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Cell Morphogenesis Focal Adhesion Assembly Neuron Development Cell Morphogenesis Adherens Junction Assembly Lamellipodium Organization Neuron Differentiation Cell-substrate Junction Assembly Cell Projection Organization Endocytosis Regulation Of Cellular Component Organization Regulation Of Axon Extension Negative Regulation Of Membrane Tubulation Post-Golgi Vesicle-mediated Transport Adherens Junction Organization System Development Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Lamellipodium Morphogenesis Generation Of Neurons Synaptic Vesicle Transport Neurogenesis Somatostatin Signaling Pathway Regulation Of Cell Size Regulation Of Cell Projection Organization Dendrite Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Cell Development Multicellular Organismal Development Axonogenesis Maintenance Of Apical/basal Cell Polarity Regulation Of Lamellipodium Morphogenesis Regulation Of Axonogenesis Regulation Of Synaptic Plasticity Cellular Component Assembly G-protein Coupled Receptor Signaling Pathway Anatomical Structure Development Receptor Localization To Synapse Dendritic Spine Maintenance	Vocalization Behavior Synapse Organization Social Behavior Regulation Of Vasoconstriction By Circulating Norepinephrine Determination Of Affect Memory Learning Sensory Processing Habituation Adult Behavior Nonassociative Learning Negative Regulation Of Peptidyl-cysteine S-nitrosylation Righting Reflex Synapse Maturation Olfactory Behavior Learning Or Memory Regulation Of Membrane Potential Cognition Cytoskeletal Anchoring At Plasma Membrane Dendritic Spine Morphogenesis Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chemosensory Behavior Long Term Synaptic Depression Dendritic Spine Development Protein Localization To Synapse Regulation Of Actin Filament-based Process Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Ventricular Cardiac Muscle Cell Action Potential Regulation Of Ion Transmembrane Transport Dendritic Spine Organization Reflex Regulation Of Membrane Repolarization Regulation Of Signaling Single-organism Behavior Positive Regulation Of Dendritic Spine Development Exploration Behavior Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential
Tagcloud ?		acetylation address carbamylated cepo display e1a epigenetic epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetic epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Difference) ?		acetylation address carbamylated cepo display e1a epo erythropoietin gap43 implications interest issue markedly modifications neurites neuronal neurons neuropsychiatric p300 possibly potentiates psd95 regulate spine subsequent transactivation upregulation yet	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Intersection) ?		epigenetic