F5 and MMRN1

Number of citations of the paper that reports this interaction (PMID 15452129)
1

Data Source:
HPRD (in vitro)

		F5	MMRN1
Gene Name		coagulation factor V (proaccelerin, labile factor)	multimerin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Platelet Alpha Granule Lumen Vesicle	Extracellular Region Platelet Alpha Granule Lumen
	Molecular Function	Serine-type Endopeptidase Activity Copper Ion Binding Protein Binding
	Biological Process	Platelet Degranulation Proteolysis Blood Coagulation Blood Circulation Platelet Activation	Platelet Degranulation Cell Adhesion Blood Coagulation Platelet Activation
Pathways		Common Pathway Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Formation of Fibrin Clot (Clotting Cascade)	Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs		Drotrecogin alfa Phenylmercury
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) D-dimer levels ( 21502573) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal atrophy ( 22745009) Uric acid levels ( 23703922) Venous thromboembolism ( 21980494 23650146 22672568)	Parkinson's disease ( 19915575)
Protein-Protein Interactions		10 interactors: CALR CSNK2A1 CTSG ELANE F10 F2 MMRN1 PROC PROS1 SERPINA3	2 interactors: CDKN2A F5
Entrez ID		2153	22915
HPRD ID		01964	03267
Ensembl ID			ENSG00000138722
Uniprot IDs		P12259	Q13201
PDB IDs		1CZS 1CZT 1CZV 1FV4 1Y61 3P6Z 3P70 3S9C
Enriched GO Terms of Interacting Partners?		Peptidyl-glutamic Acid Carboxylation Post-translational Protein Modification Response To Stress Blood Coagulation Hemostasis Negative Regulation Of Protein Metabolic Process Negative Regulation Of Blood Coagulation Leukocyte Migration Negative Regulation Of Coagulation Regulation Of Body Fluid Levels Wound Healing Negative Regulation Of Wound Healing Acute Inflammatory Response Killing By Host Of Symbiont Cells Response To Wounding Regulation Of Protein Metabolic Process Regulation Of Blood Coagulation Negative Regulation Of Proteolysis Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Processing Proteolysis Regulation Of Protein Processing Regulation Of Wound Healing Blood Coagulation, Intrinsic Pathway Peptidyl-amino Acid Modification Response To Stimulus Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Platelet Activation Fibrinolysis Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Locomotion Interaction With Symbiont Leukocyte Mediated Cytotoxicity Immune System Process Defense Response Regulation Of Proteolysis Acute-phase Response Response To Fungus Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Movement Of Cell Or Subcellular Component Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Protein Metabolic Process Positive Regulation Of Cell Proliferation	Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Macrophage Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Cell Aging Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Heterochromatin Assembly Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Sumoylation Regulation Of Smooth Muscle Cell Apoptotic Process Heterochromatin Organization Regulation Of Macrophage Apoptotic Process Positive Regulation Of Signal Transduction By P53 Class Mediator Replicative Senescence Negative Regulation Of B Cell Proliferation Regulation Of Protein Sumoylation Protein Destabilization Regulation Of Cellular Senescence Regulation Of Execution Phase Of Apoptosis Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Somatic Stem Cell Division Cellular Senescence Regulation Of Protein Export From Nucleus Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Leukocyte Apoptotic Process Protein K63-linked Ubiquitination Negative Regulation Of T Cell Differentiation Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of B Cell Activation Regulation Of Myeloid Cell Apoptotic Process Stem Cell Division Regulation Of Signal Transduction By P53 Class Mediator Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Lymphocyte Differentiation Negative Regulation Of Cell-substrate Adhesion Regulation Of Muscle Cell Apoptotic Process Regulation Of B Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Response To DNA Damage Stimulus Platelet Degranulation Cell Aging Apoptotic Mitochondrial Changes Negative Regulation Of Lymphocyte Proliferation
Tagcloud ?		alleviating average biofeedback case chemotherapy difference experiment f1 f10 f3 f4 given groups indicated intervention items others physical psychosomatic questionnaire reactions recruited relaxation scl scores seen serious training unhealthy
Tagcloud (Difference) ?		alleviating average biofeedback case chemotherapy difference experiment f1 f10 f3 f4 given groups indicated intervention items others physical psychosomatic questionnaire reactions recruited relaxation scl scores seen serious training unhealthy
Tagcloud (Intersection) ?