EPHA3 and EFNA4

Number of citations of the paper that reports this interaction (PMID 9195962)
16

Data Source:
BioGRID (pull down)

		EPHA3	EFNA4
Gene Name		EPH receptor A3	ephrin-A4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Early Endosome Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane
	Molecular Function	GPI-linked Ephrin Receptor Activity Protein Binding ATP Binding	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Cell Adhesion Axon Guidance Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Neuron Projection Development Cell Migration Peptidyl-tyrosine Phosphorylation Regulation Of Rho GTPase Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Retinoic Acid Fasciculation Of Sensory Neuron Axon Fasciculation Of Motor Neuron Axon	Cell-cell Signaling Axon Guidance Osteoclast Differentiation Bone Remodeling Ephrin Receptor Signaling Pathway
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Orofacial clefts ( 22863734)	Prostate cancer ( 23535732)
Protein-Protein Interactions		20 interactors: ABL1 ADAM10 CDKN2A CRK EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 FYN PIM1 RBM18 RUFY1 RUFY2 SRC SRPK1 STAT3 TP53	8 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 MAP2K4
Entrez ID		2042	1945
HPRD ID		01555	03224
Ensembl ID		ENSG00000044524	ENSG00000243364
Uniprot IDs		C9JXA2 P29320 Q6P4R6	P52798
PDB IDs		2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOO 2QOQ 3DZQ 3FXX 3FY2 4G2F 4GK2 4GK3 4GK4
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Differentiation Neuron Projection Development Cell Projection Morphogenesis Generation Of Neurons Cell Part Morphogenesis Neurogenesis Neuron Development Cell Development Cell Morphogenesis Movement Of Cell Or Subcellular Component Cell Projection Organization Locomotion Nervous System Development Response To External Stimulus Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Cell Differentiation Signal Transduction Developmental Process Regulation Of Cell Adhesion Signaling Cell Communication Cellular Response To Stimulus Positive Regulation Of Protein Modification Process Phosphorylation Multicellular Organismal Development Regulation Of Cell-cell Adhesion Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation System Development Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Positive Regulation Of Phosphorylation	Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Peptidyl-amino Acid Modification Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Cell Development Response To External Stimulus Neuron Development Phosphorylation Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Phosphate-containing Compound Metabolic Process Neurogenesis Fasciculation Of Motor Neuron Axon Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Cell Differentiation Fasciculation Of Sensory Neuron Axon Nervous System Development Regulation Of MAPK Cascade Regulation Of Catalytic Activity Anatomical Structure Morphogenesis System Development Regulation Of Rho GTPase Activity Cellular Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Rho Protein Signal Transduction Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Signal Transduction Developmental Process Protein Metabolic Process Signaling
Tagcloud ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd ptprt rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs
Tagcloud (Difference) ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd ptprt rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs
Tagcloud (Intersection) ?