EPHA3 and RUFY2

Number of citations of the paper that reports this interaction (PMID 11877430)
14

Data Source:
HPRD (in vivo, two hybrid)

		EPHA3	RUFY2
Gene Name		EPH receptor A3	RUN and FYVE domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Early Endosome Plasma Membrane Integral Component Of Plasma Membrane	Nucleus
	Molecular Function	GPI-linked Ephrin Receptor Activity Protein Binding ATP Binding	Metal Ion Binding
	Biological Process	Cell Adhesion Axon Guidance Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Neuron Projection Development Cell Migration Peptidyl-tyrosine Phosphorylation Regulation Of Rho GTPase Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Retinoic Acid Fasciculation Of Sensory Neuron Axon Fasciculation Of Motor Neuron Axon
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Orofacial clefts ( 22863734)
Protein-Protein Interactions		20 interactors: ABL1 ADAM10 CDKN2A CRK EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 FYN PIM1 RBM18 RUFY1 RUFY2 SRC SRPK1 STAT3 TP53	4 interactors: BMX DUSP23 EPHA3 SF3B3
Entrez ID		2042	55680
HPRD ID		01555	11526
Ensembl ID		ENSG00000044524	ENSG00000204130
Uniprot IDs		C9JXA2 P29320 Q6P4R6	B4DFR0 Q8WXA3
PDB IDs		2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOO 2QOQ 3DZQ 3FXX 3FY2 4G2F 4GK2 4GK3 4GK4
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Differentiation Neuron Projection Development Cell Projection Morphogenesis Generation Of Neurons Cell Part Morphogenesis Neurogenesis Neuron Development Cell Development Cell Morphogenesis Movement Of Cell Or Subcellular Component Cell Projection Organization Locomotion Nervous System Development Response To External Stimulus Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Cell Differentiation Signal Transduction Developmental Process Regulation Of Cell Adhesion Signaling Cell Communication Cellular Response To Stimulus Positive Regulation Of Protein Modification Process Phosphorylation Multicellular Organismal Development Regulation Of Cell-cell Adhesion Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation System Development Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Positive Regulation Of Phosphorylation	Peptidyl-tyrosine Phosphorylation Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon
Tagcloud ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd ptprt rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab rab1 rab1a rab33 rab35 rab41 rab6a rabs rbd35 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Difference) ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd ptprt rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab rab1 rab1a rab33 rab35 rab41 rab6a rabs rbd35 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Intersection) ?