EFNA4 and EPHA8

Number of citations of the paper that reports this interaction (PMID 10515610)
1

Data Source:
HPRD (in vivo)

		EFNA4	EPHA8
Gene Name		ephrin-A4	EPH receptor A8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Early Endosome Membrane Neuron Projection
	Molecular Function	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding	GPI-linked Ephrin Receptor Activity ATP Binding
	Biological Process	Cell-cell Signaling Axon Guidance Osteoclast Differentiation Bone Remodeling Ephrin Receptor Signaling Pathway	Substrate-dependent Cell Migration Cell Adhesion Axon Guidance Neuron Remodeling Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Neuron Projection Development Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		8 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 MAP2K4	11 interactors: AK4 DARS2 EFNA1 EFNA4 EFNA5 FYN G3BP1 PIK3CG PSMC5 UBC ZNF746
Entrez ID		1945	2046
HPRD ID		03224	01493
Ensembl ID		ENSG00000243364	ENSG00000070886
Uniprot IDs		P52798	P29322
PDB IDs			1UCV 1X5L 3KUL
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Peptidyl-amino Acid Modification Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Cell Development Response To External Stimulus Neuron Development Phosphorylation Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Phosphate-containing Compound Metabolic Process Neurogenesis Fasciculation Of Motor Neuron Axon Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Cell Differentiation Fasciculation Of Sensory Neuron Axon Nervous System Development Regulation Of MAPK Cascade Regulation Of Catalytic Activity Anatomical Structure Morphogenesis System Development Regulation Of Rho GTPase Activity Cellular Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Rho Protein Signal Transduction Multicellular Organismal Development Anatomical Structure Development Regulation Of Signaling Signal Transduction Developmental Process Protein Metabolic Process Signaling	Ephrin Receptor Signaling Pathway Chemotaxis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Axonogenesis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Transferase Activity Axon Development Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of MAP Kinase Activity Regulation Of Signaling Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cell Adhesion Locomotion Neuron Projection Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of Gene Expression Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Wnt Signaling Pathway DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Movement Of Cell Or Subcellular Component Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Positive Regulation Of Intracellular Signal Transduction Signal Transduction Involved In Cell Cycle Checkpoint Neuron Projection Development Regulation Of Cell Death T Cell Proliferation Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Cell Projection Morphogenesis Cell Part Morphogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Phosphorylation Signal Transduction Mitochondrial Asparaginyl-tRNA Aminoacylation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?