BNIPL and NME2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BNIPL	NME2
Gene Name		BCL2/adenovirus E1B 19kD interacting protein like	NME/NM23 nucleoside diphosphate kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Ruffle Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Intermediate Filament Focal Adhesion Membrane Lamellipodium Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Nucleoside Diphosphate Kinase Activity Protein Histidine Kinase Activity Protein Binding ATP Binding Intermediate Filament Binding Protein Kinase Binding Gamma-tubulin Binding Metal Ion Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Regulation Of Growth Rate	Negative Regulation Of Myeloid Leukocyte Differentiation Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Integrin-mediated Signaling Pathway Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Response To Amine Nucleobase-containing Small Molecule Interconversion Peptidyl-histidine Phosphorylation Hippocampus Development Response To Testosterone Cellular Response To Drug Negative Regulation Of Apoptotic Process Small Molecule Metabolic Process Positive Regulation Of Keratinocyte Differentiation Regulation Of Epidermis Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Epithelial Cell Proliferation Response To CAMP Nucleobase-containing Small Molecule Metabolic Process Cellular Response To Glucose Stimulus Cellular Response To Fatty Acid
Pathways			Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146)	Height ( 20881960)
Protein-Protein Interactions		14 interactors: ARHGAP1 BAX BCL2 BCL2L1 BNIP2 CDC42 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 SNAPIN	20 interactors: BNIPL CTBP1 DNM1 GIT2 HERC3 HERC5 HERC6 MOB4 NME1 NME1-NME2 NME3 NME4 PPP2CA RAB5A RORA RORB SVIL TBXA2R TERF1 VIM
Entrez ID		149428	4831
HPRD ID		16557	01132
Ensembl ID		ENSG00000163141	ENSG00000243678
Uniprot IDs		Q7Z465	P22392 Q6FHN3
PDB IDs			1NSK 1NUE 3BBB 3BBC 3BBF
Enriched GO Terms of Interacting Partners?		Regulation Of Mitochondrial Membrane Potential Regulation Of Protein Heterodimerization Activity Negative Regulation Of Cell Death Regulation Of Cell Death Ovarian Follicle Development Positive Regulation Of Signal Transduction Ovulation Cycle Process Negative Regulation Of Apoptotic Process Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Programmed Cell Death Female Gonad Development Regulation Of Apoptotic Process Ovulation Cycle Development Of Primary Female Sexual Characteristics Release Of Cytochrome C From Mitochondria Regulation Of Nitrogen Utilization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Regulation Of Protein Binding Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Male Sex Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Apoptotic Process Regulation Of Signal Transduction Regulation Of Cell Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Neuron Death Positive Regulation Of Cell Development Gonad Development Apoptotic Mitochondrial Changes Development Of Primary Sexual Characteristics Regulation Of Neuron Apoptotic Process Positive Regulation Of Intracellular Transport Germ Cell Development Regulation Of Signaling Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Binding Regulation Of Cellular Localization Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Neuron Death Negative Regulation Of Signal Transduction Sex Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Ribonucleotide Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Purine Nucleoside Metabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Interconversion Nucleoside Metabolic Process Nucleotide Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process Negative Regulation Of Cell Differentiation Cellular Macromolecule Catabolic Process Receptor Internalization Thromboxane A2 Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Organophosphate Metabolic Process Regulation Of Cellular Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Developmental Process Receptor Metabolic Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Regulation Of Growth Rate Telomeric Loop Formation Age-dependent Telomere Shortening Negative Regulation Of Chromosome Organization Regulation Of Circadian Rhythm Cerebellar Granule Cell Precursor Proliferation Telomere Maintenance Via Telomere Shortening Steroid Hormone Mediated Signaling Pathway Regulation Of Cellular Component Organization Cell Differentiation Cell Proliferation In Hindbrain Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Tagcloud ?		allowing alters antagonization antagonize antiapoptotic bag1 bcl bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby	17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme1 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Difference) ?		allowing alters antagonization antagonize antiapoptotic bag1 bcl bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby	17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme1 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Intersection) ?