RRAGA and PAPOLA

Number of citations of the paper that reports this interaction (PMID 14749727)
52

Data Source:
BioGRID (pull down)

		RRAGA	PAPOLA
Gene Name		Ras-related GTP binding A	poly(A) polymerase alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus EGO Complex Intracellular Membrane-bounded Organelle Gtr1-Gtr2 GTPase Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	Magnesium Ion Binding RNA Binding Polynucleotide Adenylyltransferase Activity ATP Binding Manganese Ion Binding
	Biological Process	Apoptotic Process Cell Death Cellular Response To Starvation Regulation Of Autophagy Modulation By Virus Of Host Morphology Or Physiology Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of Cytolysis Cellular Response To Amino Acid Stimulus	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Splicing Gene Expression MRNA 3'-end Processing RNA Polyadenylation
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CPSF1 CPSF4 CSTF3 IL7R NOL8 PAPOLA RPTOR RRAGC RRAGD	6 interactors: CPSF1 CPSF3 RRAGA SMAD2 SNRPA YWHAE
Entrez ID		10670	10914
HPRD ID		10205	10407
Ensembl ID		ENSG00000155876	ENSG00000090060
Uniprot IDs		Q7L523	G3XAH6 P51003
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of TOR Signaling RNA Polyadenylation Termination Of RNA Polymerase II Transcription RNA Processing Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus DNA-templated Transcription, Termination MRNA 3'-end Processing RNA Splicing RNA 3'-end Processing Response To Amino Acid MRNA Processing Cell Growth MRNA Cleavage MRNA Metabolic Process Cellular Response To Acid Chemical Cellular Response To Nutrient Levels MRNA Polyadenylation Cellular Response To Extracellular Stimulus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Response To Nutrient Levels Response To Extracellular Stimulus Cellular Response To Organonitrogen Compound Growth Regulation Of Autophagy Interleukin-7-mediated Signaling Pathway Modification By Virus Of Host MRNA Processing Regulation Of Cell Size Cellular Response To Starvation Negative Regulation Of T Cell Mediated Cytotoxicity Response To Starvation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Signal Transduction Response To Organonitrogen Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Organic Substance Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of T Cell Mediated Immunity Modulation By Virus Of Host Process Lymph Node Development Cellular Macromolecule Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of T Cell Differentiation In Thymus Macromolecule Biosynthetic Process	RNA Processing MRNA Cleavage MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Polyadenylation RNA Polyadenylation Termination Of RNA Polymerase II Transcription RNA Splicing Cellular Localization MRNA Processing MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Metabolic Process RNA 3'-end Processing Nuclear Export MRNA Transport Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone RNA Transport RNA Localization Establishment Of Localization In Cell Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytolysis Histone MRNA 3'-end Processing Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Heart Rate By Chemical Signal Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Signal Transduction SMAD Protein Complex Assembly Membrane Repolarization Paraxial Mesoderm Morphogenesis RNA Metabolic Process Nodal Signaling Pathway Intracellular Transport Gene Expression Histone MRNA Metabolic Process
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