RRAGA and CPSF1

Number of citations of the paper that reports this interaction (PMID 14749727)
52

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RRAGA	CPSF1
Gene Name		Ras-related GTP binding A	cleavage and polyadenylation specific factor 1, 160kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus EGO Complex Intracellular Membrane-bounded Organelle Gtr1-Gtr2 GTPase Complex	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	MRNA 3'-UTR Binding Protein Binding
	Biological Process	Apoptotic Process Cell Death Cellular Response To Starvation Regulation Of Autophagy Modulation By Virus Of Host Morphology Or Physiology Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of Cytolysis Cellular Response To Amino Acid Stimulus	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Transport of Mature mRNA Derived from an Intronless Transcript RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Cleavage of Growing Transcript in the Termination Region mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Intronless Pre-mRNAs Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CPSF1 CPSF4 CSTF3 IL7R NOL8 PAPOLA RPTOR RRAGC RRAGD	18 interactors: CSTF2T CSTF3 CTD GLIS2 HMOX1 IL7R MCM2 NEDD4 PAPOLA POLR2A PRRC2A REL RRAGA TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		10670	29894
HPRD ID		10205	05823
Ensembl ID		ENSG00000155876	ENSG00000071894
Uniprot IDs		Q7L523	Q10570
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of TOR Signaling RNA Polyadenylation Termination Of RNA Polymerase II Transcription RNA Processing Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus DNA-templated Transcription, Termination MRNA 3'-end Processing RNA Splicing RNA 3'-end Processing Response To Amino Acid MRNA Processing Cell Growth MRNA Cleavage MRNA Metabolic Process Cellular Response To Acid Chemical Cellular Response To Nutrient Levels MRNA Polyadenylation Cellular Response To Extracellular Stimulus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Response To Nutrient Levels Response To Extracellular Stimulus Cellular Response To Organonitrogen Compound Growth Regulation Of Autophagy Interleukin-7-mediated Signaling Pathway Modification By Virus Of Host MRNA Processing Regulation Of Cell Size Cellular Response To Starvation Negative Regulation Of T Cell Mediated Cytotoxicity Response To Starvation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Signal Transduction Response To Organonitrogen Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Organic Substance Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of T Cell Mediated Immunity Modulation By Virus Of Host Process Lymph Node Development Cellular Macromolecule Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of T Cell Differentiation In Thymus Macromolecule Biosynthetic Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Processing RNA Polyadenylation Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Termination Of RNA Polymerase II Transcription MRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Spermine Transport Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Viral Transcription Response To Cytokine Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Viral Process
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