SORBS1 and KHDRBS1

Number of citations of the paper that reports this interaction (PMID 22745667)
1

Data Source:
BioGRID (unspecified method)

		SORBS1	KHDRBS1
Gene Name		sorbin and SH3 domain containing 1	KH domain containing, RNA binding, signal transduction associated 1
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Plasma Membrane Insulin Receptor Complex Cell-cell Adherens Junction Zonula Adherens Cell-substrate Adherens Junction Focal Adhesion Nuclear Matrix Membrane Raft	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Cytoskeletal Protein Binding Protein Kinase Binding	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Muscle Contraction Cell-matrix Adhesion Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Glucose Transport Cellular Response To Insulin Stimulus Stress Fiber Assembly Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of Lipid Biosynthetic Process Focal Adhesion Assembly Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ABL1 ACTA1 ADAM15 CBL CDK6 EFNB1 FLOT1 INPPL1 INSM1 INSR KHDRBS1 MAP4K3 MLLT4 PAK2 PGR PILRA PTK2 PXN RPL4 SEMA6A SH2B2 SLC10A3 SRC TENM1 VCL	109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		10580	10657
HPRD ID		05587	03926
Ensembl ID		ENSG00000095637	ENSG00000121774
Uniprot IDs		Q9BX66	Q07666
PDB IDs		2DL3 2ECZ 2LJ0 2LJ1 2O2W 2O31 2O9S 2O9V	2XA6 3QHE
Enriched GO Terms of Interacting Partners?		Cell Development Cell Morphogenesis Involved In Differentiation Response To Stimulus Anatomical Structure Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Differentiation Anatomical Structure Morphogenesis Multicellular Organismal Development Developmental Process System Development Axonogenesis Cell Morphogenesis Signal Complex Assembly Axon Development Peptidyl-tyrosine Autophosphorylation Cell Morphogenesis Involved In Neuron Differentiation Cell Projection Organization Signal Transduction Regulation Of Cell Motility Neuron Projection Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Neuron Development Regulation Of Locomotion Regulation Of Cellular Component Movement Signaling Cell Surface Receptor Signaling Pathway Tissue Development Cell Communication Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stimulus ERBB Signaling Pathway Nervous System Development Neuron Projection Development Regulation Of Cell Proliferation Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Generation Of Neurons Cell Adhesion Adherens Junction Organization Protein Autophosphorylation Cell-substrate Adhesion Regulation Of Cell Adhesion Axon Guidance Response To Organic Substance Neurogenesis Response To Hormone Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process
Tagcloud ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa ufa underling unraveling
Tagcloud (Difference) ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa ufa underling unraveling
Tagcloud (Intersection) ?