SORBS1 and TENM1

Number of citations of the paper that reports this interaction (PMID 15777793)
8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SORBS1	TENM1
Gene Name		sorbin and SH3 domain containing 1	teneurin transmembrane protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Plasma Membrane Insulin Receptor Complex Cell-cell Adherens Junction Zonula Adherens Cell-substrate Adherens Junction Focal Adhesion Nuclear Matrix Membrane Raft	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Nuclear Matrix Nuclear Speck Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Cytoskeletal Protein Binding Protein Kinase Binding	Heparin Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Muscle Contraction Cell-matrix Adhesion Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Glucose Transport Cellular Response To Insulin Stimulus Stress Fiber Assembly Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of Lipid Biosynthetic Process Focal Adhesion Assembly Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase III Promoter Immune Response Neuropeptide Signaling Pathway Nervous System Development Negative Regulation Of Cell Proliferation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAP Kinase Activity Positive Regulation Of Filopodium Assembly Positive Regulation Of Intracellular Protein Transport
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: ABL1 ACTA1 ADAM15 CBL CDK6 EFNB1 FLOT1 INPPL1 INSM1 INSR KHDRBS1 MAP4K3 MLLT4 PAK2 PGR PILRA PTK2 PXN RPL4 SEMA6A SH2B2 SLC10A3 SRC TENM1 VCL	2 interactors: MBD1 SORBS1
Entrez ID		10580	10178
HPRD ID		05587	06669
Ensembl ID		ENSG00000095637	ENSG00000009694
Uniprot IDs		Q9BX66	B7ZMH4 Q9UKZ4
PDB IDs		2DL3 2ECZ 2LJ0 2LJ1 2O2W 2O31 2O9S 2O9V
Enriched GO Terms of Interacting Partners?		Cell Development Cell Morphogenesis Involved In Differentiation Response To Stimulus Anatomical Structure Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Differentiation Anatomical Structure Morphogenesis Multicellular Organismal Development Developmental Process System Development Axonogenesis Cell Morphogenesis Signal Complex Assembly Axon Development Peptidyl-tyrosine Autophosphorylation Cell Morphogenesis Involved In Neuron Differentiation Cell Projection Organization Signal Transduction Regulation Of Cell Motility Neuron Projection Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Neuron Development Regulation Of Locomotion Regulation Of Cellular Component Movement Signaling Cell Surface Receptor Signaling Pathway Tissue Development Cell Communication Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stimulus ERBB Signaling Pathway Nervous System Development Neuron Projection Development Regulation Of Cell Proliferation Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Generation Of Neurons Cell Adhesion Adherens Junction Organization Protein Autophosphorylation Cell-substrate Adhesion Regulation Of Cell Adhesion Axon Guidance Response To Organic Substance Neurogenesis Response To Hormone Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction	Positive Regulation Of Glycogen Biosynthetic Process Stress Fiber Assembly Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Glycogen Biosynthetic Process Focal Adhesion Assembly Positive Regulation Of Glucose Metabolic Process Regulation Of Glycogen Metabolic Process Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Glucose Import Adherens Junction Assembly Positive Regulation Of Glucose Transport Cell-substrate Junction Assembly Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Lipid Biosynthetic Process Regulation Of Glucose Import Actin Filament Bundle Assembly Glucose Transport Regulation Of Generation Of Precursor Metabolites And Energy Hexose Transport Adherens Junction Organization Regulation Of Glucose Transport Regulation Of Glucose Metabolic Process Actomyosin Structure Organization Carbohydrate Transport Regulation Of Lipid Biosynthetic Process Insulin Receptor Signaling Pathway Regulation Of Carbohydrate Metabolic Process
Tagcloud ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa ufa underling unraveling
Tagcloud (Difference) ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa ufa underling unraveling
Tagcloud (Intersection) ?