DNAJB1

Gene Name		DnaJ (Hsp40) homolog, subfamily B, member 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Extracellular Vesicular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding Hsp70 Protein Binding Unfolded Protein Binding Chaperone Binding ATPase Binding
	Biological Process	Response To Unfolded Protein Positive Regulation Of ATPase Activity Cellular Response To Heat Chaperone Mediated Protein Folding Requiring Cofactor Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		HSF1-dependent transactivation Attenuation phase Cellular response to heat stress Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Protein-protein Interactions		28 interactors: A2M AKT1 ANK2 APP BRCA1 BRMS1 CENPE CYP2C8 DNAJC3 ECSIT FANCA FANCC GLB1 HSF1 HSPA1A HSPA4 HSPA8 MAST1 NQO1 NRAS PLEKHO1 PSEN2 PTGES3 SOD1 SPP1 STUB1 TERF1 ZFP36
Entrez ID		3337
HPRD ID		05198
Ensembl ID		ENSG00000132002
Uniprot IDs		B4DX52 P25685 Q6FHS4
PDB IDs		1HDJ 2QLD 3AGX 3AGY 3AGZ
Enriched GO Terms of Interacting Partners?		Response To Stress Response To Stimulus Response To External Stimulus Response To Heat Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Temperature Stimulus Response To Organic Substance Negative Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Protein Metabolic Process Response To Unfolded Protein Cellular Response To Heat Negative Regulation Of Cellular Metabolic Process Removal Of Superoxide Radicals Cellular Response To Superoxide Protein Refolding Developmental Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Cell Morphogenesis Involved In Neuron Differentiation Response To Superoxide Response To Oxygen Radical Chemotaxis Regulation Of Cell Death Regulation Of Catalytic Activity Axon Guidance Positive Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Metabolic Process Response To Oxidative Stress Blood Coagulation Hemostasis Reactive Oxygen Species Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Differentiation Superoxide Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Kinase Activity Movement Of Cell Or Subcellular Component Axonogenesis Regulation Of Cellular Component Organization
Tagcloud ?		chaperone complement defective enlarged experimentally heat hsp hspa1a hspa6 hsps initiated interpreted keratinocytes knockin nfkappab nodes participation peroxisome physiologic ppar proliferator represses repression shock spleen stressed tnfalpha tnip1