DDX21 and PNMA2

		DDX21	PNMA2
Description		DExD-box helicase 21	PNMA family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Cytosol Membrane	Nucleolus
	Molecular Function	RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding RRNA Binding SnoRNA Binding MiRNA Binding Identical Protein Binding 7SK SnRNA Binding	Protein Binding
	Biological Process	Osteoblast Differentiation Positive Regulation Of Myeloid Dendritic Cell Cytokine Production RRNA Processing Transcription By RNA Polymerase II Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Innate Immune Response Positive Regulation Of Gene Expression, Epigenetic Defense Response To Virus	Positive Regulation Of Apoptotic Process
Pathways		B-WICH complex positively regulates rRNA expression Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Depression (quantitative trait) ( 20800221)	Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		18 interacting genes: ADAMTS14 CALM1 CSNK2A1 ERG H2AX IL7R JUN KPNA3 MTHFR PIAS1 PNMA2 SGPL1 SRPK2 SUMO2 TERF1 TERF2 TET1 UBE2I	22 interacting genes: BYSL CBX8 CCDC33 DDX21 ENKD1 FAM161A LRR1 MORF4L2 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP TOP3B TTLL10 ZNF417 ZNF587 ZNF688
Entrez ID		9188	10687
HPRD ID		05895	04915
Ensembl ID		ENSG00000165732	ENSG00000240694
Uniprot IDs		Q9NR30	Q5U5Z3 Q9UL42
PDB IDs		2M3D
Enriched GO Terms of Interacting Partners?
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