PNMA2 and DDX21

		PNMA2	DDX21
Description		PNMA family member 2	DExD-box helicase 21
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleoplasm Nucleolus Mitochondrion Cytosol Membrane
	Molecular Function	Protein Binding	RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding RRNA Binding SnoRNA Binding MiRNA Binding Identical Protein Binding 7SK SnRNA Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Osteoblast Differentiation Positive Regulation Of Myeloid Dendritic Cell Cytokine Production RRNA Processing Transcription By RNA Polymerase II Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Innate Immune Response Positive Regulation Of Gene Expression, Epigenetic Defense Response To Virus
Pathways			B-WICH complex positively regulates rRNA expression Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)	Depression (quantitative trait) ( 20800221)
Interacting Genes		22 interacting genes: BYSL CBX8 CCDC33 DDX21 ENKD1 FAM161A LRR1 MORF4L2 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP TOP3B TTLL10 ZNF417 ZNF587 ZNF688	18 interacting genes: ADAMTS14 CALM1 CSNK2A1 ERG H2AX IL7R JUN KPNA3 MTHFR PIAS1 PNMA2 SGPL1 SRPK2 SUMO2 TERF1 TERF2 TET1 UBE2I
Entrez ID		10687	9188
HPRD ID		04915	05895
Ensembl ID		ENSG00000240694	ENSG00000165732
Uniprot IDs		Q5U5Z3 Q9UL42	Q9NR30
PDB IDs			2M3D
Enriched GO Terms of Interacting Partners?
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