PNMA2 and RNF6

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		PNMA2	RNF6
Description		PNMA family member 2	ring finger protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleus Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Apoptotic Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)	Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 30297969 30718926 28869590) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		22 interacting genes: BYSL CBX8 CCDC33 DDX21 ENKD1 FAM161A LRR1 MORF4L2 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP TOP3B TTLL10 ZNF417 ZNF587 ZNF688	36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H
Entrez ID		10687	6049
HPRD ID		04915	05027
Ensembl ID		ENSG00000240694	ENSG00000127870
Uniprot IDs		Q5U5Z3 Q9UL42	A0A024RDP2 A0A0S2Z4G9 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?
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