LATS1 and ZYX

  • Number of citations of the paper that reports this interaction (PubMedID 10831611)
  • 79
  • Data Source:
  • HPRD (in vivo, in vitro)

LATS1

ZYX

Description large tumor suppressor kinase 1 zyxin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
  • Testicular germ cell tumor ( 28604728)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 28240269)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 45 interacting genes: ALPP APP AURKB CAV1 CBY2 CDC26 CDK1 CEP76 EIF4EBP1 FOXL2 FSD2 GOLGA2 KRT31 LDOC1 LIMK1 LRRK2 MAGI3 MOAP1 MOB3A MOB3B MOB3C MOB4 NEDD4 NF2 NUAK1 NUAK2 PABPN1 PPM1F PPP1R11 PPP6R3 PTEN RAC1 SMURF1 SMURF2 SSX2IP STK3 STK4 TAZ TFIP11 TRAF1 UBE2I WWOX WWP1 WWTR1 ZYX 30 interacting genes: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384
Entrez ID 9113 7791
HPRD ID 09147 03592
Ensembl ID ENSG00000131023 ENSG00000159840
Uniprot IDs O95835 Q15942 Q96AF9
PDB IDs 4ZRK 5B5W 5BRK
Enriched GO Terms of Interacting Partners?
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