ZYX and RPH3AL

Number of citations of the paper that reports this interaction (PubMedID 9367993)
17

Data Source:
HPRD (in vivo, two hybrid)

		ZYX	RPH3AL
Description		zyxin	rabphilin 3A like (without C2 domains)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Adherens Junction Focal Adhesion Phagocytic Vesicle	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Protein Binding Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Insulin Secretion Response To Drug Glucose Homeostasis Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 28240269) White blood cell count (basophil) ( 27863252)	AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
Interacting Genes		30 interacting genes: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	13 interacting genes: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX
Entrez ID		7791	9501
HPRD ID		03592	05345
Ensembl ID		ENSG00000159840	ENSG00000181031
Uniprot IDs		Q15942 Q96AF9	A8K7D5 Q9UNE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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