U2AF1 and HNRNPM

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology, biochemical)

		U2AF1	HNRNPM
Description		U2 small nuclear RNA auxiliary factor 1	heterogeneous nuclear ribonucleoprotein M
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Membrane Nuclear Matrix Paraspeckles Collagen-containing Extracellular Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of MRNA Stability Involved In Response To Oxidative Stress
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Blood and toenail selenium levels ( 25343990)	Coronary artery disease ( 29212778)
Interacting Genes		38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2	25 interacting genes: AKAP9 APC CDC5L CEACAM5 ECPAS GMCL2 HNRNPF JUN LMO2 LMO3 LYST PLRG1 PRRC2A RBM4 RBM4B SMARCB1 STAT3 TCERG1 TEKT4 U2AF1 UBC UBE2I WDR77 YWHAG ZNF207
Entrez ID		7307	4670
HPRD ID		01871	01188
Ensembl ID		ENSG00000160201	ENSG00000099783
Uniprot IDs		P0DN76 Q01081 Q7Z780	P52272 Q59ES8
PDB IDs		1JMT	2DGV 2DH9 2DO0 2OT8
Enriched GO Terms of Interacting Partners?
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