U2AF1 and SF3A3

Number of citations of the paper that reports this interaction (PubMedID 11533230)
18

Data Source:
HPRD (in vitro, in vivo)

		U2AF1	SF3A3
Description		U2 small nuclear RNA auxiliary factor 1	splicing factor 3a subunit 3
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Blood and toenail selenium levels ( 25343990)	Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2	18 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MTNR1B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212
Entrez ID		7307	10946
HPRD ID		01871	10411
Ensembl ID		ENSG00000160201	ENSG00000183431
Uniprot IDs		P0DN76 Q01081 Q7Z780	B4DW90 Q12874
PDB IDs		1JMT	2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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