HNRNPM and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology, biochemical)

		HNRNPM	U2AF1
Description		heterogeneous nuclear ribonucleoprotein M	U2 small nuclear RNA auxiliary factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Membrane Nuclear Matrix Paraspeckles Collagen-containing Extracellular Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of MRNA Stability Involved In Response To Oxidative Stress	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		25 interacting genes: AKAP9 APC CDC5L CEACAM5 ECPAS GMCL2 HNRNPF JUN LMO2 LMO3 LYST PLRG1 PRRC2A RBM4 RBM4B SMARCB1 STAT3 TCERG1 TEKT4 U2AF1 UBC UBE2I WDR77 YWHAG ZNF207	38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2
Entrez ID		4670	7307
HPRD ID		01188	01871
Ensembl ID		ENSG00000099783	ENSG00000160201
Uniprot IDs		P52272 Q59ES8	P0DN76 Q01081 Q7Z780
PDB IDs		2DGV 2DH9 2DO0 2OT8	1JMT
Enriched GO Terms of Interacting Partners?
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