MOAP1 and LATS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MOAP1	LATS1
Description		modulator of apoptosis 1	large tumor suppressor kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol	Spindle Pole Microtubule Organizing Center Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Estrogen Receptor Binding
	Biological Process	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Sister Chromatid Segregation Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Protein Phosphorylation Hormone-mediated Signaling Pathway Peptidyl-serine Phosphorylation Keratinocyte Differentiation Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Cellular Protein Localization Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Protein Complex Assembly Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cytoplasmic Sequestering Of Protein Cell Division Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)	Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Testicular germ cell tumor ( 28604728)
Interacting Genes		18 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FZR1 LATS1 MAGEH1 MBIP PNMA5 RASSF1 THOC1 TNFRSF10A TNFRSF1A UBQLN4 UBR5	45 interacting genes: ALPP APP AURKB CAV1 CBY2 CDC26 CDK1 CEP76 EIF4EBP1 FOXL2 FSD2 GOLGA2 KRT31 LDOC1 LIMK1 LRRK2 MAGI3 MOAP1 MOB3A MOB3B MOB3C MOB4 NEDD4 NF2 NUAK1 NUAK2 PABPN1 PPM1F PPP1R11 PPP6R3 PTEN RAC1 SMURF1 SMURF2 SSX2IP STK3 STK4 TAZ TFIP11 TRAF1 UBE2I WWOX WWP1 WWTR1 ZYX
Entrez ID		64112	9113
HPRD ID		17580	09147
Ensembl ID		ENSG00000165943	ENSG00000131023
Uniprot IDs		Q96BY2	O95835
PDB IDs			4ZRK 5B5W 5BRK
Enriched GO Terms of Interacting Partners?
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