RARS1 and EPRS1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, biochemical)
HPRD (two hybrid)

		RARS1	EPRS1
Description		arginyl-tRNA synthetase 1	glutamyl-prolyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	TRNA Binding Arginine-tRNA Ligase Activity Protein Binding ATP Binding Arginine Binding Cadherin Binding	Glutamate-tRNA Ligase Activity Proline-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding RNA Stem-loop Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation	TRNA Aminoacylation For Protein Translation Glutamyl-tRNA Aminoacylation Prolyl-tRNA Aminoacylation Negative Regulation Of Translation Cellular Response To Insulin Stimulus Protein-containing Complex Assembly Cellular Response To Interferon-gamma Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation tRNA modification in the nucleus and cytosol
Drugs			Glutamic Acid L-Proline '5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine '5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine
Diseases
GWAS
Interacting Genes		3 interacting genes: AIMP1 EPRS1 QARS1	12 interacting genes: AIMP2 ARL4D DUS2 EEF1D ESR1 HSP90AA1 IARS1 NEDD4 NELFCD RARS1 SYNCRIP TAB1
Entrez ID		5917	2058
HPRD ID		00142	00703
Ensembl ID		ENSG00000113643	ENSG00000136628
Uniprot IDs		P54136	P07814
PDB IDs		4Q2T 4Q2X 4Q2Y 4R3Z 4ZAJ	1FYJ 4HVC 4K86 4K87 4K88 5A1N 5A34 5A5H 5BMU 5V58 5VAD 5Y6L 6IY6
Enriched GO Terms of Interacting Partners?
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