EPRS1 and ARL4D

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EPRS1	ARL4D
Description		glutamyl-prolyl-tRNA synthetase 1	ADP ribosylation factor like GTPase 4D
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex GAIT Complex Ribonucleoprotein Complex	Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	Glutamate-tRNA Ligase Activity Proline-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding RNA Stem-loop Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Glutamyl-tRNA Aminoacylation Prolyl-tRNA Aminoacylation Negative Regulation Of Translation Cellular Response To Insulin Stimulus Protein-containing Complex Assembly Cellular Response To Interferon-gamma Regulation Of Long-chain Fatty Acid Import Into Cell	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation tRNA modification in the nucleus and cytosol
Drugs		Glutamic Acid L-Proline '5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine '5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine
Diseases
GWAS
Interacting Genes		12 interacting genes: AIMP2 ARL4D DUS2 EEF1D ESR1 HSP90AA1 IARS1 NEDD4 NELFCD RARS1 SYNCRIP TAB1	22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119
Entrez ID		2058	379
HPRD ID		00703	02842
Ensembl ID		ENSG00000136628	ENSG00000175906
Uniprot IDs		P07814	P49703
PDB IDs		1FYJ 4HVC 4K86 4K87 4K88 5A1N 5A34 5A5H 5BMU 5V58 5VAD 5Y6L 6IY6
Enriched GO Terms of Interacting Partners?
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