RAB5C and INCA1

Number of citations of the paper that reports this interaction (PubMedID 21750715)
15

Data Source:
BioGRID (pull down)

		RAB5C	INCA1
Description		RAB5C, member RAS oncogene family	inhibitor of CDK, cyclin A1 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Lipid Droplet Plasma Membrane Endomembrane System Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding
	Biological Process	Intracellular Protein Transport Rab Protein Signal Transduction Neutrophil Degranulation Plasma Membrane To Endosome Transport	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737)	Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: APP APPL2 CCR10 DGKI EEA1 GLP1R HOXB13 HRAS INCA1 KRT15 RABAC1 RAPGEFL1 RBSN RIN2 RIN3 SGSM3 SLC27A2 TBC1D15 TBC1D17	39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1
Entrez ID		5878	388324
HPRD ID		04947	17150
Ensembl ID		ENSG00000108774	ENSG00000196388
Uniprot IDs		A0A024R1U4 P51148	Q0VD86
PDB IDs		4KYI
Enriched GO Terms of Interacting Partners?
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