RAB5C and RAPGEFL1

		RAB5C	RAPGEFL1
Description		RAB5C, member RAS oncogene family	Rap guanine nucleotide exchange factor like 1
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GO Annotations	Cellular Component	Lysosomal Membrane Endosome Lipid Droplet Plasma Membrane Endomembrane System Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Intracellular Protein Transport Rab Protein Signal Transduction Neutrophil Degranulation Plasma Membrane To Endosome Transport	G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Nervous System Development
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737)	Asthma ( 31619474)
Interacting Genes		19 interacting genes: APP APPL2 CCR10 DGKI EEA1 GLP1R HOXB13 HRAS INCA1 KRT15 RABAC1 RAPGEFL1 RBSN RIN2 RIN3 SGSM3 SLC27A2 TBC1D15 TBC1D17	3 interacting genes: APP MLH1 RAB5C
Entrez ID		5878	51195
HPRD ID		04947	17954
Ensembl ID		ENSG00000108774	ENSG00000108352
Uniprot IDs		A0A024R1U4 P51148	B4DGK9 F5H2D5 Q9UHV5
PDB IDs		4KYI	2DHZ
Enriched GO Terms of Interacting Partners?
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