PTBP2 and PUF60

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		PTBP2	PUF60
Description		polypyrimidine tract binding protein 2	poly(U) binding splicing factor 60
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nucleoplasm Cell Junction
	Molecular Function	RNA Binding MRNA Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	MRNA Splicing, Via Spliceosome Apoptotic Process
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)
Interacting Genes		20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1	34 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 ERG FBXO7 FHL2 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		58155	22827
HPRD ID		12233	18051
Ensembl ID		ENSG00000117569	ENSG00000179950
Uniprot IDs		B4DSS8 B4DSU5 Q9UKA9	Q9UHX1
PDB IDs		2CQ1 2MJU 4CQ1	2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ
Enriched GO Terms of Interacting Partners?
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