PTBP2 and KHDRBS3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		PTBP2	KHDRBS3
Description		polypyrimidine tract binding protein 2	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Binding MRNA Binding	RNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)	Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1	33 interacting genes: BAHD1 CACNA1A CCDC33 DMRT3 FBXO7 FUS HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LNX1 MARK4 NCOA5 NELFB NUDT18 PPP1R13B PRMT1 PRPF31 PSMF1 PTBP2 RBBP6 RBM7 RBMX RBMY1A1 SGSM2 SIAH1 SNRPC SRSF9 U2AF2 YTHDC1 ZNF408 ZNF688
Entrez ID		58155	10656
HPRD ID		12233	10007
Ensembl ID		ENSG00000117569	ENSG00000131773
Uniprot IDs		B4DSS8 B4DSU5 Q9UKA9	O75525
PDB IDs		2CQ1 2MJU 4CQ1	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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