PUF60 and H1-2

Number of citations of the paper that reports this interaction (PubMedID 18258596)
47

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		PUF60	H1-2
Description		poly(U) binding splicing factor 60	H1.2 linker histone, cluster member
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cell Junction	Nucleosome Nuclear Chromatin Nucleus Nuclear Euchromatin Transcriptionally Active Chromatin
	Molecular Function	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Regulation Of Transcription, DNA-templated Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination Histone H3-K4 Trimethylation Histone H3-K27 Trimethylation
Pathways		mRNA Splicing - Major Pathway	Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes		34 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 ERG FBXO7 FHL2 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16	30 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 RBM39 SNCA VHL WDR12 WDR5 YBX1
Entrez ID		22827	3006
HPRD ID		18051	07514
Ensembl ID		ENSG00000179950	ENSG00000187837
Uniprot IDs		Q9UHX1	P16403
PDB IDs		2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ
Enriched GO Terms of Interacting Partners?
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