PUF60 and U2AF2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid, biochemical, two hybrid)
HPRD (two hybrid)

		PUF60	U2AF2
Description		poly(U) binding splicing factor 60	U2 small nuclear RNA auxiliary factor 2
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GO Annotations	Cellular Component	Nucleoplasm Cell Junction	Commitment Complex Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Prespliceosome U2AF
	Molecular Function	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding	RNA Binding Protein Binding Poly-pyrimidine Tract Binding Enzyme Binding Pre-mRNA 3'-splice Site Binding C2H2 Zinc Finger Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Negative Regulation Of Protein Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677)
Interacting Genes		34 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 ERG FBXO7 FHL2 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16	47 interacting genes: APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA IL7R KHDC4 KHDRBS3 LURAP1 MAP1B OTUB2 PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TLE5 TOP1 U2AF1 WT1 ZRSR2
Entrez ID		22827	11338
HPRD ID		18051	01872
Ensembl ID		ENSG00000179950	ENSG00000063244
Uniprot IDs		Q9UHX1	P26368
PDB IDs		2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ	1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW 4TU7 4TU8 4TU9 5EV1 5EV2 5EV3 5EV4 5W0G 5W0H
Enriched GO Terms of Interacting Partners?
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