NGLY1 and GRM7

NGLY1

GRM7

Description N-glycanase 1 glutamate metabotropic receptor 7
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute kidney injury in coronary artery bypass surgery (creatinine rise) ( 26083657)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) ( 23648065)
  • Airway imaging phenotypes ( 26030696)
  • Chronotype ( 30696823)
  • Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
  • Daytime sleep phenotypes ( 27126917)
  • Diastolic blood pressure ( 30224653)
  • Early response to risperidone in schizophrenia ( 26856250)
  • Major depressive disorder (broad) ( 20038947)
  • Night sleep phenotypes ( 27126917)
  • Orofacial clefts ( 22419666)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Panic disorder ( 19165232)
  • Personality traits in bipolar disorder ( 21368711)
  • Plasma clusterin levels ( 26545630)
  • Recurrent major depressive disorder ( 29317602)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Systemic sclerosis ( 30247649)
  • Telomere length ( 30185882)
  • Urate levels in lean individuals ( 25811787)
  • Uterine fibroid number (single vs multiple) ( 30196971)
  • Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes 19 interacting genes: APP FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NSFL1C OPA3 PROC RAD23A RAD23B SH3BP1 SRPK2 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP 15 interacting genes: CALM1 CALM2 CALM3 FLNA GNAQ GRIP1 GRIPAP1 NGLY1 PICK1 SDCBP TUBA1A TUBA1B TUBA3C TUBA4A TUBA8
Entrez ID 55768 2917
HPRD ID 10118 04979
Ensembl ID ENSG00000151092 ENSG00000196277
Uniprot IDs Q96IV0 B2R693 B9EGG9 Q14831 Q59G95
PDB IDs 2CCQ 2CM0 3MQ4 5C5C
Enriched GO Terms of Interacting Partners?
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