NGLY1 and SH3BP1

		NGLY1	SH3BP1
Description		N-glycanase 1	SH3 domain binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Exocyst Phagocytic Cup Intracellular Nucleus Cytosol Adherens Junction Bicellular Tight Junction Lamellipodium Cell Leading Edge
	Molecular Function	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding Semaphorin Receptor Binding Rac GTPase Binding
	Biological Process	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation	Phagocytosis, Engulfment Actin Filament Organization Cell Migration Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Cell Junction Assembly Regulation Of Rac Protein Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Small GTPase Mediated Signal Transduction Semaphorin-plexin Signaling Pathway
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: APP FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NSFL1C OPA3 PROC RAD23A RAD23B SH3BP1 SRPK2 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP	12 interacting genes: ABL1 CRK HCK NGLY1 POT1 RAC1 RHOA SRC SUN2 SYNJ1 TERF1 TRIP10
Entrez ID		55768	23616
HPRD ID		10118	10227
Ensembl ID		ENSG00000151092	ENSG00000100092
Uniprot IDs		Q96IV0	A0A2X0SFX7 Q9Y3L3
PDB IDs		2CCQ 2CM0	4J9D 4J9F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?