NGLY1 and RAD23B

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		NGLY1	RAD23B
Description		N-glycanase 1	RAD23 homolog B, nucleotide excision repair protein
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex
	Molecular Function	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding
	Biological Process	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Protein Folding Spermatogenesis Protein Deubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Global Genome Nucleotide-excision Repair Cellular Response To Interleukin-7
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle	N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS			Body mass index ( 20966902) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)
Interacting Genes		19 interacting genes: APP FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NSFL1C OPA3 PROC RAD23A RAD23B SH3BP1 SRPK2 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP	23 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HMGB1 MLH1 MPG NGLY1 PAQR3 PAX3 PNMA5 PSMC2 PSMD4 PUF60 RPA1 TDG UBA2 UBB UBC UBE3A XPC ZFAND5
Entrez ID		55768	5887
HPRD ID		10118	06772
Ensembl ID		ENSG00000151092	ENSG00000119318
Uniprot IDs		Q96IV0	B7Z4W4 P54727
PDB IDs		2CCQ 2CM0	1P1A 1PVE 1UEL
Enriched GO Terms of Interacting Partners?
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