GRM7 and GRIPAP1

Number of citations of the paper that reports this interaction (PubMedID 11891216)
43

Data Source:
HPRD (two hybrid, in vitro)

		GRM7	GRIPAP1
Description		glutamate metabotropic receptor 7	GRIP1 associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Cortex Integral Component Of Membrane Axon Dendrite Asymmetric Synapse Dendritic Shaft Receptor Complex Postsynaptic Membrane Presynaptic Active Zone	Nucleoplasm Cytosol Cell Junction Axon Dendrite Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Blood Microparticle Postsynaptic Recycling Endosome Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane
	Molecular Function	Group III Metabotropic Glutamate Receptor Activity Glutamate Receptor Activity Adenylate Cyclase Inhibitor Activity Glutamate Binding Serine Binding	Molecular_function Protein Binding
	Biological Process	Behavioral Fear Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Sensory Perception Of Sound Negative Regulation Of Glutamate Secretion Regulation Of Cyclase Activity Regulation Of Synaptic Transmission, Glutamatergic	Biological_process Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Regulation Of Modification Of Synaptic Structure
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs		Glutamic Acid
Diseases
GWAS		Acute kidney injury in coronary artery bypass surgery (creatinine rise) ( 26083657) Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) ( 23648065) Airway imaging phenotypes ( 26030696) Chronotype ( 30696823) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Early response to risperidone in schizophrenia ( 26856250) Major depressive disorder (broad) ( 20038947) Night sleep phenotypes ( 27126917) Orofacial clefts ( 22419666) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Panic disorder ( 19165232) Personality traits in bipolar disorder ( 21368711) Plasma clusterin levels ( 26545630) Recurrent major depressive disorder ( 29317602) Response to fenofibrate (total cholesterol levels) ( 27002377) Systemic sclerosis ( 30247649) Telomere length ( 30185882) Urate levels in lean individuals ( 25811787) Uterine fibroid number (single vs multiple) ( 30196971) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		15 interacting genes: CALM1 CALM2 CALM3 FLNA GNAQ GRIP1 GRIPAP1 NGLY1 PICK1 SDCBP TUBA1A TUBA1B TUBA3C TUBA4A TUBA8	17 interacting genes: ARL15 CASP3 CCNB3 CCNT1 GPR173 GRIA1 GRIP1 GRM7 HSPB1 MAGED4B MAP3K1 RAB4A SMAD2 SMURF1 SPP1 TCEA2 TES
Entrez ID		2917	56850
HPRD ID		04979	02325
Ensembl ID		ENSG00000196277	ENSG00000068400
Uniprot IDs		B2R693 B9EGG9 Q14831 Q59G95	Q4V328
PDB IDs		3MQ4 5C5C
Enriched GO Terms of Interacting Partners?
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