RRN3 and MYO1C

Number of citations of the paper that reports this interaction (PubMedID 15558034)
128

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		RRN3	MYO1C
Description		RRN3 homolog, RNA polymerase I transcription factor	myosin IC
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Stress Fiber Cell Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Filamentous Actin Vesicle Ruffle Membrane Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase I Core Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity	Microfilament Motor Activity Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Ral GTPase Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly In Utero Embryonic Development Transcription Initiation From RNA Polymerase I Promoter Nucleolus Organization Cytoplasm Organization Cell Proliferation Positive Regulation Of Neuron Projection Development Ribosome Biogenesis Positive Regulation Of Transcription, DNA-templated Homeostasis Of Number Of Cells Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription, Initiation	Protein Targeting Protein Targeting To Membrane Actin Filament Organization Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Gene Expression, Epigenetic MRNA Transport Cellular Response To Interferon-gamma Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Bicellular Tight Junction Assembly
Pathways		RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)	Atrial fibrillation ( 30061737) Pulse pressure ( 30578418)
Interacting Genes		10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C	5 interacting genes: BAZ1B CBL KHDRBS1 PTEN RRN3
Entrez ID		54700	4641
HPRD ID		12004	09411
Ensembl ID		ENSG00000085721	ENSG00000197879
Uniprot IDs		B7ZB55 F5H148 Q9NYV6	O00159
PDB IDs			4BYF
Enriched GO Terms of Interacting Partners?
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