PDE9A and LAGE3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PDE9A	LAGE3
Description		phosphodiesterase 9A	L antigen family member 3
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process	TRNA Processing Biological_process Positive Regulation Of Transcription By RNA Polymerase II TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		cGMP effects	tRNA modification in the nucleus and cytosol
Drugs		Caffeine Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil
Diseases
GWAS		Perceived unattractiveness to mosquitoes ( 28199695)
Interacting Genes		20 interacting genes: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NLA PCNT PHYHIPL SULT1E1 TFAP4 TRIM32 TRPV6 UTP23	2 interacting genes: KRT40 PDE9A
Entrez ID		5152	8270
HPRD ID		09115	02087
Ensembl ID		ENSG00000160191	ENSG00000196976
Uniprot IDs		A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083	Q14657
PDB IDs		2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N	6GWJ
Enriched GO Terms of Interacting Partners?
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