PDE9A and SULT1E1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PDE9A	SULT1E1
Description		phosphodiesterase 9A	sulfotransferase family 1E member 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm	Cytosol Nuclear Membrane
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Estrone Sulfotransferase Activity Steroid Binding Protein Binding Sulfotransferase Activity Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity
	Biological Process	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process	Ethanol Catabolic Process Estrogen Catabolic Process Steroid Metabolic Process Estrogen Metabolic Process Positive Regulation Of Fat Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		cGMP effects	Cytosolic sulfonation of small molecules
Drugs		Caffeine Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil	Cyclizine Adenosine-3'-5'-Diphosphate 3'-Phosphate-Adenosine-5'-Phosphate Sulfate 3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol
Diseases
GWAS		Perceived unattractiveness to mosquitoes ( 28199695)	Heel bone mineral density ( 30598549)
Interacting Genes		20 interacting genes: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NLA PCNT PHYHIPL SULT1E1 TFAP4 TRIM32 TRPV6 UTP23	13 interacting genes: BMPR2 COPS6 EEF1A1 ENOX1 ERG28 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119
Entrez ID		5152	6783
HPRD ID		09115	08966
Ensembl ID		ENSG00000160191	ENSG00000109193
Uniprot IDs		A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083	P49888 Q53X91
PDB IDs		2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N	1G3M 1HY3 4JVL 4JVM 4JVN
Enriched GO Terms of Interacting Partners?
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