PDE9A and KRTAP10-8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PDE9A	KRTAP10-8
Description		phosphodiesterase 9A	keratin associated protein 10-8
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm	Cytosol Keratin Filament
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process	Keratinization
Pathways		cGMP effects	Keratinization
Drugs		Caffeine Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil
Diseases
GWAS		Perceived unattractiveness to mosquitoes ( 28199695)
Interacting Genes		20 interacting genes: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NLA PCNT PHYHIPL SULT1E1 TFAP4 TRIM32 TRPV6 UTP23	165 interacting genes: - ACY3 ADAMTSL3 ADAMTSL4 AEN ALDH3B1 ALPI AMMECR1 APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 CARHSP1 CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MOBP MTA1 MXI1 NAB2 NAXD NECTIN3 NOTCH2NLA NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SHFL SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPACA9 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TLE5 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21
Entrez ID		5152	386681
HPRD ID		09115	11194
Ensembl ID		ENSG00000160191	ENSG00000187766
Uniprot IDs		A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083	P60410
PDB IDs		2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N
Enriched GO Terms of Interacting Partners?
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