NONO and NUPR1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
16

Data Source:
BioGRID (two hybrid)

		NONO	NUPR1
Description		non-POU domain containing octamer binding	nuclear protein 1, transcriptional regulator
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Offspring birth weight ( 31043758) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1	21 interacting genes: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP
Entrez ID		4841	26471
HPRD ID		02098	17814
Ensembl ID		ENSG00000147140	ENSG00000176046
Uniprot IDs		A0A0S2Z4Z9 Q15233	A0A024QZC4 O60356
PDB IDs		3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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