NONO and SYNPO

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NONO	SYNPO
Description		non-POU domain containing octamer binding	synaptopodin
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex	Stress Fiber Nucleus Cytosol Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Dendritic Spine Perikaryon Spine Apparatus Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding	Actin Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Visual Learning Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Modification Of Dendritic Spine Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Postsynaptic Cytosolic Calcium Concentration Spine Apparatus Assembly
Pathways
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401)
Interacting Genes		42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1	7 interacting genes: G3BP1 MAGI1 NCK1 NCK2 NONO YWHAG YWHAZ
Entrez ID		4841	11346
HPRD ID		02098	12179
Ensembl ID		ENSG00000147140	ENSG00000171992
Uniprot IDs		A0A0S2Z4Z9 Q15233	Q8N3V7
PDB IDs		3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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