NONO and C11orf68

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NONO	C11orf68
Description		non-POU domain containing octamer binding	chromosome 11 open reading frame 68
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181)
Interacting Genes		42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1	7 interacting genes: CSDE1 EIF4H KCNE3 NONO REL SDCBP SH3GL3
Entrez ID		4841	83638
HPRD ID		02098	12553
Ensembl ID		ENSG00000147140	ENSG00000175573
Uniprot IDs		A0A0S2Z4Z9 Q15233	Q9H3H3
PDB IDs		3SDE 5IFM	1ZTP 2Q4K
Enriched GO Terms of Interacting Partners?
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