LDLRAD1 and BNIP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LDLRAD1	BNIP3
Description		low density lipoprotein receptor class A domain containing 1	BCL2 interacting protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Postsynaptic Density Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process		Autophagy Of Mitochondrion Response To Hypoxia Apoptotic Process Cell Death Granzyme-mediated Apoptotic Signaling Pathway Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Viral Process Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Negative Regulation Of Cell Death Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Mitochondrial Outer Membrane Permeabilization Toxin Transport Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Aerobic Respiration Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: ADGRG7 BNIP3 BNIP3L GIMAP5 LAPTM5 MAL MALL MARCHF2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B	21 interacting genes: BCL2 BCL2L1 BCL2L2 BNIP3L CD47 CLEC7A CLN8 CREB3 FATE1 HIF1A HIVEP1 KTN1 LDLRAD1 LMNA MAP1LC3B NCBP1 OPA1 RHEB TGM2 TMEM11 TUBGCP2
Entrez ID		388633	664
HPRD ID		17372	04482
Ensembl ID		ENSG00000203985	ENSG00000176171
Uniprot IDs		Q5T700	Q12983 Q6NVY4
PDB IDs			2J5D 2KA1 2KA2
Enriched GO Terms of Interacting Partners?
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