BNIP3 and CD47

Number of citations of the paper that reports this interaction (PubMedID 12690108)
23

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		BNIP3	CD47
Description		BCL2 interacting protein 3	CD47 molecule
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Postsynaptic Density Dendrite Integral Component Of Mitochondrial Outer Membrane Mitochondrial Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding	Protein Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Apoptotic Process Cell Death Granzyme-mediated Apoptotic Signaling Pathway Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Viral Process Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Negative Regulation Of Cell Death Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Mitochondrial Outer Membrane Permeabilization Toxin Transport Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Aerobic Respiration Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Reactive Oxygen Species Metabolic Process	Inflammatory Response Integrin-mediated Signaling Pathway Opsonization Positive Regulation Of Cell Proliferation Response To Bacterium Cell Migration Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Interferon-gamma Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Monocyte Extravasation Neutrophil Degranulation Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Leukocyte Migration Positive Regulation Of Stress Fiber Assembly Monocyte Aggregation Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways			Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)	Bipolar disorder ( 31043756) Body mass index ( 25673413) Regular attendance at a religious group ( 29970889)
Interacting Genes		21 interacting genes: BCL2 BCL2L1 BCL2L2 BNIP3L CD47 CLEC7A CLN8 CREB3 FATE1 HIF1A HIVEP1 KTN1 LDLRAD1 LMNA MAP1LC3B NCBP1 OPA1 RHEB TGM2 TMEM11 TUBGCP2	12 interacting genes: BNIP3 EPB42 FAS GNAI1 ITGAV P2RY2 PTK2 RHAG SIRPA SYNE4 THBS1 UBQLN1
Entrez ID		664	961
HPRD ID		04482	03017
Ensembl ID		ENSG00000176171	ENSG00000196776
Uniprot IDs		Q12983 Q6NVY4	A0A0A1TSG4 Q08722
PDB IDs		2J5D 2KA1 2KA2	2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU
Enriched GO Terms of Interacting Partners?
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