LDLRAD1 and VTI1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LDLRAD1	VTI1B
Description		low density lipoprotein receptor class A domain containing 1	vesicle transport through interaction with t-SNAREs 1B
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity
	Biological Process		Platelet Degranulation Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Blood protein levels ( 30072576)
Interacting Genes		16 interacting genes: ADGRG7 BNIP3 BNIP3L GIMAP5 LAPTM5 MAL MALL MARCHF2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B	13 interacting genes: CLINT1 CREB3 GOLGB1 KRTAP10-7 LDLRAD1 LMNA PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59
Entrez ID		388633	10490
HPRD ID		17372	04440
Ensembl ID		ENSG00000203985	ENSG00000100568
Uniprot IDs		Q5T700	Q9UEU0
PDB IDs			2V8S
Enriched GO Terms of Interacting Partners?
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