LDLRAD1 and OLFM4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LDLRAD1	OLFM4
Description		low density lipoprotein receptor class A domain containing 1	olfactomedin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Extracellular Space Nucleoplasm Mitochondrion Cytosol Plasma Membrane Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Azurophil Granule Intercellular Bridge Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Protein Binding	Catalytic Activity Structural Molecule Activity Protein Binding Cadherin Binding
	Biological Process		Cell Adhesion Regulation Of Necrotic Cell Death Regulation Of Apoptotic Process Neutrophil Degranulation Regulation Of Phagocytosis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Extravasation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26961502 24861553 25673413 28448500 25953783) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Cerebrospinal P-tau181p levels ( 28247064) Childhood body mass index ( 26604143) Depression ( 29700475) Hip circumference ( 25673412) Immune response to anthrax vaccine ( 22658931) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661) Waist circumference ( 25673412)
Interacting Genes		16 interacting genes: ADGRG7 BNIP3 BNIP3L GIMAP5 LAPTM5 MAL MALL MARCHF2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B	5 interacting genes: APP C3 KASH5 LDLRAD1 SYNE4
Entrez ID		388633	10562
HPRD ID		17372	06580
Ensembl ID		ENSG00000203985	ENSG00000102837
Uniprot IDs		Q5T700	A0A024QZ95 Q6UX06
PDB IDs
Enriched GO Terms of Interacting Partners?
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