HSPB2 and ACTC1

Number of citations of the paper that reports this interaction (PubMedID 26465331)
5

Data Source:
BioGRID (two hybrid)

		HSPB2	ACTC1
Description		heat shock protein family B (small) member 2	actin alpha cardiac muscle 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse
	Molecular Function	Protein Binding Enzyme Activator Activity	ATP Binding ATPase Activity Myosin Binding
	Biological Process	Response To Unfolded Protein Positive Regulation Of Catalytic Activity	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration
Pathways			Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS			Axial length ( 24144296) Refractive error ( 20835239)
Interacting Genes		89 interacting genes: A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BEX4 BGN C1QA CAPZA2 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HSPB3 HSPB8 LGALS1 MAPKAPK5 MB MCCC2 MDH1 MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PGM1 PKP2 PPM1K RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 TATDN1 TCAP THEMIS2 THUMPD2 TNNI3 TTN TXNIP UBL5 WDR1 ZNF335	39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1
Entrez ID		3316	70
HPRD ID		03712	00015
Ensembl ID		ENSG00000170276	ENSG00000159251
Uniprot IDs		A8KAH6 Q16082	B3KPP5 P68032
PDB IDs		6F2R
Enriched GO Terms of Interacting Partners?
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