HSPB2 and MYH6

Number of citations of the paper that reports this interaction (PubMedID 26465331)
5

Data Source:
BioGRID (two hybrid)

		HSPB2	MYH6
Description		heat shock protein family B (small) member 2	myosin heavy chain 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Stress Fiber Cytosol Muscle Myosin Complex Myosin Complex Myofibril Sarcomere Z Disc Myosin Filament
	Molecular Function	Protein Binding Enzyme Activator Activity	Microfilament Motor Activity Calmodulin Binding ATP Binding ATPase Activity Myosin Phosphatase Activity Protein Kinase Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Response To Unfolded Protein Positive Regulation Of Catalytic Activity	In Utero Embryonic Development Regulation Of The Force Of Heart Contraction Regulation Of Heart Rate Protein Dephosphorylation Muscle Contraction Striated Muscle Contraction Adult Heart Development Visceral Muscle Development Regulation Of Heart Contraction Regulation Of Blood Pressure Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Myofibril Assembly Regulation Of ATPase Activity Sarcomere Organization ATP Metabolic Process Cardiac Muscle Fiber Development Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Regulation Of Heart Growth
Pathways			Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect
GWAS			Aortic coarctation ( 29590334) Atrial fibrillation ( 30061737) Diastolic blood pressure ( 30578418) Electrocardiographic traits ( 20062063) Heart rate ( 23583979) P wave duration ( 28794112) P wave terminal force ( 28794112) PR interval ( 30046033) Pulse pressure ( 28135244 27618447 27618448 30578418) Resting heart rate ( 29769521 23183192 27798624 28270201 20639392) RR interval (heart rate) ( 30679814) Systolic blood pressure ( 27618447)
Interacting Genes		89 interacting genes: A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BEX4 BGN C1QA CAPZA2 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HSPB3 HSPB8 LGALS1 MAPKAPK5 MB MCCC2 MDH1 MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PGM1 PKP2 PPM1K RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 TATDN1 TCAP THEMIS2 THUMPD2 TNNI3 TTN TXNIP UBL5 WDR1 ZNF335	6 interacting genes: CALCOCO1 CALCOCO2 ESR1 HSPB2 POLR2A TRIM63
Entrez ID		3316	4624
HPRD ID		03712	01171
Ensembl ID		ENSG00000170276	ENSG00000197616
Uniprot IDs		A8KAH6 Q16082	P13533
PDB IDs		6F2R
Enriched GO Terms of Interacting Partners?
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