ACTC1 and KAT14

Number of citations of the paper that reports this interaction (PubMedID 30890647)
1

Data Source:
BioGRID (pull down)

		ACTC1	KAT14
Description		actin alpha cardiac muscle 1	lysine acetyltransferase 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	Histone Acetyltransferase Activity Protein Binding LIM Domain Binding
	Biological Process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	G2/M Transition Of Mitotic Cell Cycle Histone Acetylation Histone H3 Acetylation
Pathways		Striated Muscle Contraction	HATs acetylate histones
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Axial length ( 24144296) Refractive error ( 20835239)	Thyroglobulin plasma levels ( 30929638)
Interacting Genes		39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	7 interacting genes: ACTC1 CSRP2 H3C1 H4-16 H4C1 MBIP TRIM27
Entrez ID		70	57325
HPRD ID		00015	16765
Ensembl ID		ENSG00000159251	ENSG00000149474
Uniprot IDs		B3KPP5 P68032	Q9H8E8
PDB IDs
Enriched GO Terms of Interacting Partners?
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