CHMP2A and USP54

Number of citations of the paper that reports this interaction (PubMedID 19302785)
8

Data Source:
BioGRID (pull down)

		CHMP2A	USP54
Description		charged multivesicular body protein 2A	ubiquitin specific peptidase 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin ESCRT III Complex Cell Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding	Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly	Protein Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: CHD3 CHMP3 CYP4F2 DOCK8 E2F4 EIF2B5 ITGA5 KERA MAPKAPK3 MITD1 NCOA1 NOL4 SLC25A1 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B ZNF32	21 interacting genes: ARID5B ATN1 ATXN1 CDK19 CFAP70 CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 EIF4E2 FAM149B1 FUT11 HK1 MSS51 MSX2 NXT2 PLCD1 SAMD8 TTYH1 UBC
Entrez ID		27243	159195
HPRD ID		12520	15641
Ensembl ID		ENSG00000130724	ENSG00000166348
Uniprot IDs		A0A024R4S0 O43633	B7Z7X1 Q70EL1
PDB IDs
Enriched GO Terms of Interacting Partners?
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